Objective fatigue measurement is an unmet clinical need:

1. Fatigue is a common symptom in many diseases
2. An indication that something is wrong => early risk prediction & prevention
3. Essential for the management of affected patients to optimise care => improve intervention
4. It has detrimental effects beyond disease (e.g. the elderly, road accidents, workplace accidents)

Fatigue is prevalent in many illnesses, a common complaint among the elderly population and causes of human related accidents:

Indication

Prevalence Rate

Reference

Cancer

59-100%

Pubmed PMID: 21831025

Cardiovascular disease

30-70%

Pubmed PMID: 14597589

Multiple Sclerosis

65-97%

Pubmed PMID: 30507270

Elderly population

22%

Pubmed: PMID: 31446404

Road accidents

20-30%

Pubmed: PMID: 25532512

Aviation accidents

80%

Pubmed: PMID: 16733255

General medical practice

25%

Pubmed: PMID: 11993585